N-terminal acetylation is catalyzed by a highly conserved family of N-terminal acetyltransferases (NATs). NATs activity is mostly mediated by five distinct but highly conserved complexes (NatA to NatE) bearing distinct subunits and having different substrate specificities. Additionally, we recently identified NatF, a higher eukaryote-specific NAT complex whose enzymatic activity was responsible for a significant shift … Continue reading Protein N-terminal Acetylation, Germline development, and Mitosis