Tânia Ferreira, Pedro Prudêncio, Rui Gonçalo Martinho. Drosophila Protein Kinase N (Pkn) is a negative regulator of actin-myosin activity during oogenesis. Developmental Biology (2014) 10.1016/j.ydbio.2014.08.008. Abstract: Nurse cell dumping is an actin–myosin based process, where 15 nurse cells of a given egg chamber contract and transfer their cytoplasmic content through the ring canals into the growing […]
CONTINUE READINGhttp://www.ncbi.nlm.nih.gov/pubmed/24909324
CONTINUE READINGhttp://www.ncbi.nlm.nih.gov/pubmed/24835465
CONTINUE READINGhttp://www.rtp.pt/play/p401/e152806/cientifica-mente
CONTINUE READINGhttp://elifesciences.org/content/3/e02407
CONTINUE READINGRequirement for highly efficient pre-mRNA splicing during Drosophila early embryonic development (2014). Leonardo Gastón Guilgur, Pedro Prudêncio, Daniel Sobral, Denisa Liszekova, André Rosa, Rui Gonçalo Martinho. eLife 2014;3:e02181. Abstract Drosophila syncytial nuclear divisions limit transcription unit size of early zygotic genes. As mitosis inhibits not only transcription, but also pre-mRNA splicing, we reasoned that constraints […]
CONTINUE READINGDual mode of embryonic development is highlighted by expression and function of Nasonia pair-rule gene Miriam I Rosenberg, Ava E Brent, François Payre, Claude Desplan Embryonic anterior–posterior patterning is well understood in Drosophila, which uses ‘long germ’ embryogenesis, in which all segments are patterned before cellularization. In contrast, most insects use ‘short germ’ embryogenesis, wherein […]
CONTINUE READINGThe Earliest Transcribed Zygotic Genes Are Short, Newly Evolved, and Different across Species Patricia Heyn, Martin Kircher, Andreas Dahl, Janet Kelso, Pavel Tomancak, Alex T Kalinka, Karla M Neugebauer The transition from maternal to zygotic control is fundamental to the life cycle of all multicellular organisms. It is widely believed that genomes are transcriptionally inactive […]
CONTINUE READINGPereira P.A., Navarro-Costa P., Martinho R.G. and Becker J.D. (2014). Evolutionarily conserved mechanisms of male germline development in flowering plants and animals. Biochemical Society Transactions (in Press). Abstract Sexual reproduction is the main reproductive strategy of the overwhelming majority of eukaryotes. This suggests that the last eukaryotic common ancestor was able to reproduce sexually. Sexual […]
CONTINUE READINGThelial is a targeted carcinoma drug discovery and development company. For more info check here: http://www.thelial.com/
CONTINUE READING